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1

Solution structures of the Shewanella woodyi HâNOX protein in the presence and absence of soluble guanylyl cyclase stimulator IWP â051

Chen, ChengâYu, Lee, Woonghee, Renhowe, Paul A., Jung, Joon, Montfort, William R.

Journal:

Protein Science

Year:

2020

File:

PDF, 2.31 MB

2020

2

ChemInform Abstract: Investigations of a Nucleophilic Alaninol Synthon Derived from Serine.

Mukund P. Sibi, Drew Rutherford, Paul A. Renhowe, Biqin Li

Journal:

Year:

1999

File:

PDF, 40 KB

1999

3

ChemInform Abstract: Advances in Solid-Supported Organic Synthesis Methods, 1998 to 1999

John M. Nuss, Paul A. Renhowe

Journal:

Year:

2000

File:

PDF, 24 KB

2000

4

ChemInform Abstract: A Practical Entry to the Crambescidin Family of Guanidine Alkaloids. Enantioselective Total Syntheses of Ptilomycalin A, Crambescidin 657 and Its Methyl Ester (Neofolitispates 2), and Crambescidin 800.

D. Scott Coffey, Andrew I. McDonald, Larry E. Overman, Michael H. Rabinowitz, Paul A. Renhowe

Journal:

Year:

2000

File:

PDF, 30 KB

2000

5

Design and structure–activity relationship of heterocyclic analogs of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones as inhibitors of receptor tyrosine kinases

Kelly Frazier, Elisa Jazan, Christopher M. McBride, Sabina Pecchi, Paul A. Renhowe, Cynthia M. Shafer, Clarke Taylor, Dirksen Bussiere, Molly Min He, Johanna M. Jansen, Gena Lapointe, Sylvia Ma, Jayes

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 137 KB

english, 2006

6

Design and structure–activity relationship of 3-benzimidazol-2-yl-1H-indazoles as inhibitors of receptor tyrosine kinases

Christopher M. McBride, Paul A. Renhowe, Carla Heise, Johanna M. Jansen, Gena Lapointe, Sylvia Ma, Ramon Piñeda, Jayesh Vora, Marion Wiesmann, Cynthia M. Shafer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 166 KB

english, 2006

7

Identification and structure–activity relationship of 2-morpholino 6-(3-hydroxyphenyl) pyrimidines, a class of potent and selective PI3 kinase inhibitors

Sabina Pecchi, Paul A. Renhowe, Clarke Taylor, Susan Kaufman, Hanne Merritt, Marion Wiesmann, Kevin R. Shoemaker, Mark S. Knapp, Elizabeth Ornelas, Thomas F. Hendrickson, Wendy Fantl, Charles F. Voliv

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.16 MB

english, 2010

8

Design and synthesis of 5,6-fused heterocyclic amides as Raf kinase inhibitors

Savithri Ramurthy, Mina Aikawa, Payman Amiri, Abran Costales, Ahmad Hashash, Johanna M. Jansen, Song Lin, Sylvia Ma, Paul A. Renhowe, Cynthia M. Shafer, Sharadha Subramanian, Leonard Sung, Joelle Verh

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 491 KB

english, 2011

9

LHMDS mediated tandem acylation–cyclization of 2-aminobenzenecarbonitriles with 2-benzymidazol-2-yl acetates: a short and efficient route to the synthesis of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones

William R. Antonios-McCrea, Kelly A. Frazier, Elisa M. Jazan, Timothy D. Machajewski, Christopher M. McBride, Sabina Pecchi, Paul A. Renhowe, Cynthia M. Shafer, Clarke Taylor

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 102 KB

english, 2006

10

A new nucleophilic alaninol synthon from serine

Mukund P. Sibi, Paul A. Renhowe

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 319 KB

english, 1990

11

3-Benzimidazol-2-yl-1H-indazoles as potent c-ABL inhibitors

Christopher M. McBride, Paul A. Renhowe, Thomas G. Gesner, Johanna M. Jansen, Julie Lin, Sylvia Ma, Yasheen Zhou, Cynthia M. Shafer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 148 KB

english, 2006

12

4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors

Zhi-Jie Ni, Paul Barsanti, Nathan Brammeier, Anthony Diebes, Daniel J. Poon, Simon Ng, Sabina Pecchi, Keith Pfister, Paul A. Renhowe, Savithri Ramurthy, Allan S. Wagman, Dirksen E. Bussiere, Vincent L

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 155 KB

english, 2006

13

Design and synthesis of 6,6-fused heterocyclic amides as raf kinase inhibitors

Savithri Ramurthy, Abran Costales, Johanna M. Jansen, Barry Levine, Paul A. Renhowe, Cynthia M. Shafer, Sharadha Subramanian

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 562 KB

english, 2012

14

Enantioselective total synthesis of (+)-isolaurepinnacin

Berger, Daniel, Overman, Larry E., Renhowe, Paul A.

Journal:

Journal of the American Chemical Society

Year:

1993

Language:

english

File:

PDF, 266 KB

english, 1993

15

Total Synthesis of (+)-Isolaurepinnacin. Use of Acetal-Alkene Cyclizations To Prepare Highly Functionalized Seven-Membered Cyclic Ethers

Berger, Daniel, Overman, Larry E., Renhowe, Paul A.

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 403 KB

english, 1997

16

Enantioselective Total Synthesis of (-)-Ptilomycalin A

Overman, Larry E., Rabinowitz, Michael H., Renhowe, Paul A.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 283 KB

english, 1995

17

Investigations of a Nucleophilic Alaninol Synthon Derived from Serine

Sibi, Mukund P., Rutherford, Drew, Renhowe, Paul A., Li, Biqin

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 257 KB

english, 1999

18

Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors

Renhowe, Paul A., Pecchi, Sabina, Shafer, Cynthia M., Machajewski, Timothy D., Jazan, Elisa M., Taylor, Clarke, Antonios-McCrea, William, McBride, Christopher M., Frazier, Kelly, Wiesmann, Marion, Lap

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 326 KB

english, 2009

19

Regioselective Opening of Terminal Epoxides with 2-(Trialkylsilyl)allyl Organometallic Reagents

Overman, Larry E., Renhowe, Paul A.

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 493 KB

english, 1994

20

Design and Synthesis of Orally Bioavailable Benzimidazole Reverse Amides as Pan RAF Kinase Inhibitors

Subramanian, Sharadha, Costales, Abran, Williams, Teresa E., Levine, Barry, McBride, Christopher M., Poon, Daniel, Amiri, Payman, Renhowe, Paul A., Shafer, Cynthia M., Stuart, Darrin, Verhagen, Joelle

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 566 KB

english, 2014

21

A novel thermolytic annulation of an oxazolidinone: an enantiospecific synthesis of (-)-slaframine

Sibi, Mukund P., Christensen, James W., Li, Biqin, Renhowe, Paul A.

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 253 KB

english, 1992

22

A Practical Entry to the Crambescidin Family of Guanidine Alkaloids. Enantioselective Total Syntheses of Ptilomycalin A, Crambescidin 657 and Its Methyl Ester (Neofolitispates 2), and Crambescidin 800

Coffey, D. Scott, McDonald, Andrew I., Overman, Larry E., Rabinowitz, Michael H., Renhowe, Paul A.

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 503 KB

english, 2000

23

Design, Structure–Activity Relationship, and in Vivo Characterization of the Development Candidate NVP-HSP990

McBride, Christopher M., Levine, Barry, Xia, Yi, Bellamacina, Cornelia, Machajewski, Timothy, Gao, Zhenhai, Renhowe, Paul, Antonios-McCrea, William, Barsanti, Paul, Brinner, Kristin, Costales, Abran,

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

24

Correction to Design and Synthesis of Orally Bioavailable Benzimidazole Reverse Amides as Pan RAF Kinase Inhibitors

Subramanian, Sharadha, Costales, Abran, Williams, Teresa E., Levine, Barry, McBride, Christopher M., Poon, Daniel, Amiri, Payman, Renhowe, Paul A., Shafer, Cynthia M., Stuart, Darrin, Verhagen, Joelle

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

File:

PDF, 114 KB

2014

25

[Annual Reports in Medicinal Chemistry] Volume 36 || Chapter 11. Growth factor receptor kinases in cancer

Renhowe, Paul A.

Year:

2001

Language:

english

File:

PDF, 845 KB

english, 2001

26

Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase

Wales, Jessica A, Chen, Cheng-Yu, Breci, Linda, Weichsel, Andrzej, Bernier, Sylvie G, Sheppeck, James E, Solinga, Robert, Nakai, Takashi, Renhowe, Paul A, Jung, Joon, Montfort, William R.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 9.03 MB

english, 2017

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